Things are still pretty much the same, the eye continues to look horrible but Pika is not showing any indications that he is in pain. We did notice a small blister under his eye on Friday that seemed to be bothering him, so the serrapeptase treatment was suspended for a few days to allow the lesion to heal. I'll reassess this afternoon and decide then whether to start the enzyme treatment again.
Last week I read an interesting paper describing the use of a NOX inhibitor as a therapy for liver fibrosis. From what I could understand, NOX (NADPH oxidase) is part of an inter-cellular signaling pathway that results in the recruitment of macrophages to areas of inflammation to lay down scar tissue. If it works as a treatment for out of control scar tissue formation in the liver, would it do the same thing for a myofibroblastic sarcoma? So far I've only looked at treatments to reverse the damage after it's already been done, I would love to find a way to stop the damage before it happens. The problem is, I don't really know that much about the particular NOX inhibitor that was used and since it is still experimental I highly doubt I could obtain any for my own purposes. There are some NOX inhibitors that are available that I've been looking at, but they are expensive and I haven't been able to find papers that would be helpful in determining the correct dosage for a cat. For now this will have to join the ALK inhibitor I was looking at as something that may hold promise, but which I will not likely be able to try.
An article about the NOX inhibor treatment can be found here:
http://www.news-medical.net/news/20120808/Study-reports-new-potential-NOX-inhibitor-therapy-for-liver-fibrosis.aspx
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